Serial samples must be collected over several days to evaluate baseline and peak total estrogen levels. I feel fine I think. Once you have determined if your estrogen is high or low you can then start to target your treatment. The serum testing is not helpful if you use creams as estrogen levels do not rapidly cross into the serum. You can read more about supplements designed to help manage low estrogen here. The principal cause of low estrogen is menopause which tends to occur in the fifth decade of life. Dr. Westin Childs is a Doctor of Osteopathic Medicine. Some women may be taking medications or supplements which interfere with estrogen activity. Men with slightly higher levels of estrogen doubled their risk of coronary artery disease. These estrogens are then cut up and metabolized into smaller fragments by the liver and each of these fragments also has an impact on estrogen receptors in the body. Males may experience sexual problems and enlarged breasts, while females may experience weight gain and menstrual complications. ... To interpret test results use the reference range in the laboratory report. The relationship between the ovaries and normal estrogen production is well-known: ... creating total havoc for the body's hormone levels. Some other treatments may include estrogen replacement therapy and alternative medications. The evaluation of your estrogen should always be in the setting of whatever symptoms you are experiencing. Harvard Health Letter. An imbalance in estrogen levels can cause many problems and symptoms. Welcome to my website! The National Library of Medicine (NLM), on the NIH campus in Bethesda, Maryland, is the world's largest biomedical library and the developer of electronic information services that delivers data to millions of scientists, health professionals and members of the public around the globe, every day. These three factions are all measured during estrogen testing. Copyright © 2021 Leaf Group Ltd., all rights reserved. Normal estrogen levels in males may slow that process. Restartmed.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. A reference range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval). Oral birth control medication blocks the natural production of FSH and LH from the pituitary gland which can effectively shut off the production of endogenous progesterone and estrogen in your body (8). But just realize that there are MANY other "estrogens" floating around in your body which are not being tested and which may have an impact on your body. Normal estrogen results depend upon the sex and age of the person being tested. Symptoms of high estrogen levels are anxiety, depression, mood swings and insomnia. It is well known that estrogen levels vary based on the month (4) (estradiol goes up and down based on the female menstrual cycle) and based on your age (5) (menopause results in very low estradiol levels). Measuring estrogen levels can provide important information about fertility, pregnancy, menstrual cycles, and other health conditions. Certain hormones have the ability to sit on and activate estrogen receptors in the body which turn on genetic function (1). You are the single best way to determine if your levels are normal or abnormal. High estrogen levels can cause a range of symptoms. He is trained in Internal Medicine, Functional Medicine, and Integrative Medicine. The total estrogen lab test is a great tool to measure and monitor estrogen levels and distinguish any abnormal levels and imbalances. The normal range of estrogen varies depending upon the patient's age. The first is to always order estradiol in combination with progesterone. This ratio of 10:1 only holds true during the mid-luteal phase of the menstrual cycle (days 19-21). * These statements have not been evaluated by the Food and Drug Administration. Death rates increased by 133% when estradiol levels were less than 12.… Evaluate for ovarian estrogen producing tumor in the premenarcheal and postmenopausal female; evaluate estrogen excess in males. With experience in management and customer service, business is a primary focus of her writing. I am a Doctor (D.O.) These conditions, coupled with the fact that low progesterone can also cause high estrogen symptoms, may explain why this particular condition is much more common in menstruating women. Estrogen replacement therapy has seen a decrease in use due to the possible link between it and uterine cancer, heart disease and stroke. Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline. What is considered a "normal estrogen level"? Atherosclerosis or hardening of the arteries may lead to heart attacks and strokes. Estrogen analysis may be helpful in establishing time of ovulation and optimal time for conception. And because each woman has her own "normal" it's best to consider ratios rather than absolute numbers. They also are important for many other, non-gender-specific processes, including growth, nervous system maturation, bone metabolism/remodeling, and endothelial responsiveness. Absolute numbers (either high or low) tend to have value when they fall outside of the reference range provided by the lab company, but you will find that most women who suffer from symptoms often have "normal" lab tests. The use of certain supplements ( such as low progesterone may mimic the symptoms of low estrogen estrogen is helpful! 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